Figure 4.

Effect of C/EBPβ and Ras^V12 on cell growth and cytoskeletal reorganization. (A) Growth curves of wild-type and C/EBPβ^−/− MEFs transduced with C/EBPβ and/or Ras^V12. Each value was normalized to the cell number at day 0 (postselection). A representative example is shown from at least two independent experiments performed in duplicate. Bottom panel: Western blot analysis of C/EBPβ expression. (B) Cell morphology of control and C/EBPβ-transduced C/EBPβ^−/− MEFs. Cells were photographed at day 6 postselection. The cells were also stained for stress fibers using FITC-conjugated phalloidin (right panels). A representative example from two independent experiments is shown; photographs were taken at the same magnification.