Skip to main content
. Author manuscript; available in PMC: 2005 Sep 21.
Published in final edited form as: Viral Immunol. 2005;18(1):41–78. doi: 10.1089/vim.2005.18.41

FIG. 10.

FIG. 10

Effect of the administration (ip) of an IL-6–Ab on plasma ACTH (A) and corticosterone (B) levels in WT and CRH-KO mice after injection with MCMV (5 × 104 PFU/mouse) or vehicle. The IL-6-Ab (1 mg/mouse) was administered 16 h prior to the peak MCMV-induced corticosterone response (20 h post-infection). Trunk blood was collected from mice at 36 h post-infection (n = 4–8 animals per group). *p < 0.05; ***p < 0.001 (t test for WT/MCMV/IL-6–Ab vs. WT/media/IgG); compared with media/IgG group within genotype. #p < 0.05; ###p < 0.001; compared with MCMV/IgG group within genotype. +p < 0.05; ++p < 0.01 (t test); +++p < 0.001; compared with respective WT group. Two-way ANOVA was used (unless otherwise indicated). Because of limited amounts of Ab, a media/IL-6–Ab group was not included in this experiment. Reprinted by permission from Silverman et al. (273).