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. Author manuscript; available in PMC: 2005 Sep 21.
Published in final edited form as: Viral Immunol. 2005;18(1):41–78. doi: 10.1089/vim.2005.18.41

FIG. 6.

FIG. 6

Kinetics and magnitudes of endogenous glucocorticoid responses vary depending on viral challenge. Serum corticosterone responses to polyinosinic-polycytidylic acid (poly I:C) administration and during viral infections are shown. Mice were injected with 100 μg poly I:C (A) or infected with 2 × 104 PFU of lymphocytic choriomeningitis virus (LCMV) clone E350 (B), 5 × 104 PFU murine cytomegalovirus (MCMV) (C), or 1 × 106 PFU LCMV clone 13 (D). Serum samples were collected under low-stress conditions during the morning (36 h post MCMV-infection) and examined for levels of serum corticosterone. Harvests were at indicated times following treatment or infection. Data are presented as means ± SEM. Reprinted with modifications by permission from Miller et al. (188,189).