Figure 5.
Effect of apoptotic neutrophils on monocytic IL-10 production in response to P. gingivalis LPS. In response to P. gingivalis LPS, IL-10 production from monocytes was significantly increased when cocultured with apoptotic neutrophils (*P <0.05). This effect was also significant compared to monocytes cultured with fresh neutrophils at 48 and 72 hours while there was no difference at 24 hours (†P <0.05). Fresh neutrophils led to a significant increase in IL-10 generation from monocytes only at the end of 72 hours ( ‡P <0.05).