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. 2002 Feb 19;99(5):3087–3092. doi: 10.1073/pnas.261715099

Figure 3.

Figure 3

(A and B) Circulating ACTH is somewhat increased in the PC2 null but is dramatically increased in the 7B2 null (A); corticosterone is increased only in the 7B2 null (B). Serum for both assays was prepared from 5-week-old animals killed by rapid decapitation at the same time of day. Note that circulating ACTH levels in the PC2 and 7B2 WT mice were not significantly different, whereas 7B2 null male and female ACTH levels were significantly increased over WT (***, P < 0.0001, Student's t test). A significant difference between PC2 null male animals and controls is shown by *** (P < 0.0001); differences between PC2 null females and controls are indicated by a single asterisk (*) and reached a significance of only P < 0.012.