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. 2025 Jun 23;17(13):2095. doi: 10.3390/cancers17132095
A
AZA Azacitidine
ALCL Anaplastic large cell lymphoma
ALL Acute Lymphoblastic Leukemia
AML Acute Myeloid Leukemia
ANKRD26 Ankyring Repeat Domain Containing protein 26
APL Acute promyelocytic leukemia
ARF Alternative Reading Frame
ASXL1 Additional Sex Combs-like 1
ATO Arsenic trioxide
ATRA All-trans retinoic acid
B
BCL-2 B-cell lymphoma-2
BCL-XL B-cell lymphoma extra large
BCOR BCL6 corepressor
BCORL1 BCL6 corepressor-like 1
BM Bone Marrow
BRAF V-Raf Murine Sarcoma Viral Oncogene Homolog B1
C
CAR Chimeric Antigen Receptor
CBF Core Binding Factor
CBL Casitas B-lineage Lymphoma
CD Cluster of Differentiation
CEBPA CCAAT enhancer binding protein alpha
CH Clonal Hematopoiesis
CNS Central Nervous System
CR Complete Remission
CRISPR Clustered Regularly Interspaced Short Palindromic Repeats
CSF3R Colony Stimulating Factor 3 receptor
D
DDX41 DEAD Box helicase 41
DNA Deoxyribonucleic acid
DNMT3A DNA (cytosine-5)-methyltransferase 3A
E
EFS Event-Free Survival
ELN European Leukemia Net
ETV6 ETS variant transcription factor 6
EZH2 Enhancer of Zeste Homolog 2
F
FAB French–American–British Classification
FDA Food and Drug Administration
FLT3-ITD FMS-like tyrosine kinase 3 internal tandem duplication
FLT3-TKD FMS-like tyrosine kinase 3 tyrosine kinase domain
FOXM1 Forkhead box M1
G
GATA2 GATA Binding protein 2
GPR56 G protein coupled receptor 56
GO Gemtuzumab ozogamicin
H
HDAC Histone Deacetylase
HiDAC High-Dose Cytarabine
HLA Human Leukocyte Antigen
HLF Hepatic Leukemia Factor
HMA Hypomethylating agent
HSCT Hematopoietic Stem Cell Transplantation
HOX Homeobox
I
ICC International Consensus Classification
IDAC Intermediate Dose Cytarabine
IDH1 Isocitrate Dehydrogenase 1
IDH 2 Isocitrate Dehydrogenase 2
IHC Immunohistochemistry
J
JAK2 Janus Kinase 2
K
KMT2A Lysine Methyltransferase 2A
KIT KIT protooncogene, receptor tyrosine kinase
KPT-330 Selinexor
KPT-8602 Eltaxenor
KO Knockout
KO-539 Ziftomenib
KRAS Kirsten rat sarcoma viral oncogene homolog
M
MDS Myelodysplastic Syndrome
MCL1 Myeloid Cell Leukemia sequence 1
MEIS1 Myeloid Ecotropic viral Integration site 1
MEIS-SMC4 Myeloid Ecotropic viral Integration site 1-Structural Maintenance of Chromosome 4
MLL Mixed Lineage Leukemia
MPNs Myeloproliferative Neoplasms
MRGs Myelodysplasia related gene mutations
MRD Measurable Residual Disease
MRD-LL Measurable Residual Disease at Low Level
N
NCCN National Comprehensive Cancer Network
ND Newly Diagnosed
NF1 Neurofibromatosis type 1
NGS Next-Generation Sequencing
NHL Non-Hodgkin lymphoma
NK Natural Killer
NPM1 Nucleophosmin 1
NPM1wt NPM1 wild type
NRAS Neuroblastoma RAS viral oncogene homolog
O
ORR Overall Response Rate
OS Overall Survival
P
PB Peripheral Blood
PBX3 Pre-B-cell leukemia transcription factor 3
PD-1 Programmed (Cell) Death 1
PD-L1 Programmed (Cell) Death Ligand 1
PFS Progression-free survival
PHF6 Plant Homeodomain Finger Protein 6
PPM1D Protein phosphatase magnesium-dependent 1 delta
PRC1 Polycomb repressive complex 1
PRC2 Polycomb repressive complex 2
PTPN11 Protein Tyrosine Phosphatase Non-Receptor Type 11
R
RNA Ribonucleic acid
RP2D Recommended phase 2 dose
R/R AML Relapsed or refractory acute myeloid leukemia
RT-qPCR Quantitative Reverse Transcription Polymerase Chain Reaction
RUNX1 Runt-related transcription factor 1
S
SETBP1 Set Binding Protein 1
SF3B1 Splicing Factor 3B Subunit 1
SINE Selective Inhibitors of Nuclear Export
SNDX-5613 Revumenib
SRSF2 Serine/Arginine-rich Splicing Factor 2
STAG2 Stromal Antigen 2
STAT5 Signal transducer and activator of transcription 5
T
TCR T-cell receptor
TET2 TET methylcytosine dioxygenase 2
TP53 Tumor Protein p53
U
U2AF1 U2 small nuclear RNA auxiliary factor 1
V
VAF Varied Allele Frequency
VEN Venetoclax
W
WHO World Health Organization
WT1 Wilms Tumor 1
X
XPO1 Exportin 1
Z
ZRSR2 Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2