Table 4.
Response to NACT observed in various studies (22,27–31)
Year | Institute | Neoadjuvant chemotherapy used | Number of patients | Response % | |
De Lena et al.[29] | 1979 | Southeastern cancer study group | FAC | 14 | 80 |
Morrow et al.[23] | 1980 | Guy's hospital | AV | 12 | 83 |
Aisner et al.[27] | 1982 | University of Maryland | FAC | 27 | 74 |
Sataloff et al.[30] | 1994 | Thomas Jefferson University Hospital | CMF | 189 | 85 |
Swain et al.[28] | 1995 | M.D. Anderson cancer center | FAC | 174 | 88 |
Singh et al.[22] | 1996 | PGI, Chandigarh India | CMF | 38 | 75.7 |
Present Study | 2003–2004 | VMMC, Safdarjang Hospital New Delhi | FAC | 50 | 60 |
AV: [Adriamycin, Vincristine]
CMF: [Cyclophosphamide. Methotrexate, 5-fluouracil]
FAC [5-fluouracil, Adriamycin, Cyclophosphamide]