Skip to main content
. 2025 Jul 7;17(13):2256. doi: 10.3390/cancers17132256
ADC Antibody-Drug Conjugate
AE Adverse Event
ASCL1 Achaete-Scute Family BHLH Transcription Factor 1
BCL-2 B-cell lymphoma 2
BiTE Bispecific T-cell Engager
B7-H3 B7 Homolog 3/CD276
cCRT Concurrent Chemoradiotherapy
CI Confidence Interval
CNS Central Nervous System
CRPC Castration-Resistant Prostate Cancer
CRS Cytokine-Release Syndrome
CRT Chemoradiotherapy
CT Computed Tomography
CTFI Chemotherapy-Free Interval
CTLA-4 Cytotoxic T-Lymphocyte Antigen 4
CTX Chemotherapy
DLCO Diffusing Capacity of the Lung for Carbon Monoxide
DLL3 Delta-like protein 3
DLT Dose-Limiting Toxicity
DCR Disease Control Rate
DOR Duration Of Response
ED-SCLC Extensive-Disease small cell lung cancer
EMA National Comprehensive Cancer Network
ESMO European Society For Medical Oncology
EZH2 Enhancer of Zeste Homolog 2
FDA United States Food and Drug Administration
FDG-PET Fluorodeoxyglucose Positron Emission Tomography
FEV1 Forced Expiratory Volume in 1 Second
FL Follicular Lymphoma
HR Hazard Ratio
ICANS Immune Effector Cell-Associated Neurotoxicity Syndrome
IGFR1 Insulin-like Growth Factor 1 Receptor
ILD Interstitial Lung Disease
IO Immunotherapy
irAE Immune-Related Adverse Events
LD-SCLC Limited-Disease small cell lung cancer
LDH Lactate Dehydrogenase
MRI Magnetic Resonance Imaging
MYC Myelocytomatosis oncogene
NCAM Neural Cell Adhesion Molecule, also known as CD56
NCCN National Comprehensive Cancer Network
NEC Neuroendocrine Carcinoma
NEURO1 Neurogenic Differentiation Factor 1
NOTCH Neurogenic locus notch homolog (NOTCH) signaling pathway gene
NSCLC Non-Small Cell Lung Cancer
NSE Neuron-Specific Enolase
ORR Objective Response Rate
OS Overall Survival
PARP Poly ADP-ribose Polymerase
PARPi Poly ADP-ribose Polymerase inhibitor
PCI Prophylactic Cranial Irradiation
PD-1 Programmed Cell Death Protein 1
PD-L1 Programmed Death-Ligand 1
PFS Progression-Free Survival
POU2F3 POU Class 2 Homeobox 3
PR Partial Response
PROTAC Proteolysis-Targeting Chimera
PS Performance Status
RB1 Retinoblastoma 1
SCLC Small cell lung cancer
SD Stable Disease
SEZ6 Seizure-Related 6 Homolog
SG Sacituzumab Govitecan
SIADH Syndrome of Inappropriate Antidiuretic Hormone Secretion
SLFN11 Schlafen Family Member 11
SOC Standarf Of Care
TEAE Treatment-Emergent Adverse Event
TKI Tyrosine Kinase Inhibitor
TP53 Tumor protein p53
TRAE Treatment-Related Adverse Events
Trop-2 Tumor-associated calcium signal transducer 2
TTF-1 Thyroid Transcription Factor-1
UICC Union for International Cancer Control
VC Vital Capacity
VEGF Vascular Endothelial Growth Factor
VOD Veno-Occlusive Disease
YAP1 Yes-associated protein 1