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. 2025 Jul 1;17(13):2215. doi: 10.3390/cancers17132215
HNC Head neck cancer
TAAs Tumor-associated antigens
MHC Major histocompatibility complex
TME Tumor microenvironment
T-Reg Regulatory T cells
NK Natural killer
ADCC Antibody-dependent cellular cytotoxicity
EBV Epstein–Barr virus
HPV Human papillomavirus
CAR-T Chimeric antigen receptor T cell
PD-1 Programmed Death-1
PD-L1 Programmed Death-Ligand 1
HNSCC Head and neck squamous cell carcinoma
CPS Combined positive score
PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses
CTLs Cytotoxic T lymphocytes
ICIs Immune checkpoint inhibitors
CAF Cancer-associated fibroblasts
PTT Photothermal therapy
TIM-3 Immunoglobulin and Mucin Domain-Containing 3
iCAR-T Inhibitory CAR-T
EPHB4 Ephrin type-B receptor 4
Eph Erythropoietin-producing hepatocellular
OCSCC Oral squamous cell carcinoma
PDX Patient-derived xenograft
IHC Immunoistochemistry
MUC1 Mucin 1
HIF-1 Hypoxia inducible factor
RTKs Receptor tyrosine kinases
Cad Oncolytic adenovirus
HGF Hepatocyte growth factor
NPC Nasopharyngeal carcinoma
GvHD Graft-versus-host disease
DLTs Dose-limiting toxicities
EGFR Epidermal growth factor receptor
HER2 Human EGFR Related 2
HER3 Human EGFR Related 2
HER4 Human EGFR Related 4