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Regulation of AMPA receptor phosphorylation by serotonin (100 μM) in vitro. The amounts of phospho-Ser-831–GluR1 (Left) and phospho-Ser-845–GluR1 (Right) in extracts of slices from WT (black bars) and DARPP-32 KO (white bars) mice were quantified by densitometry. Data represents means ± SE for three to ten experiments. *, P < 0.05, **, P < 0.01, ***, P < 0.001 compared with control; #, P < 0.05, ##, P < 0.01 compared with serotonin in WT, Student's t test.
