Behavioral responses to treatment with PCA and 5-HTP in WT and
DARPP-32 KO mice. Effects of (Left) PCA (4 mg/kg) and
(Right) 5-HTP (50 mg/kg) on total locomotion
(Upper) and stereotypic movements
(Lower) in WT and DARPP-32 KO mice. Data represent
means ± SE for 6–10 mice per group. *,
P < 0.05; **, P
< 0.01; ***, P < 0.001
compared with saline-treated mice; ###, P < 0.001;
##, P < 0.01; #, P < 0.05
compared with WT mice given the same treatment; two-way ANOVA followed
by Duncan's test.