A549	Adenocarcinoma human alveolar basal epithelial cells
AGRF	Australian Genomes Research Facility
ANOVA	Analysis of variance
APS	Ammonium persulfate
ARACNe	Algorithm for the Reconstruction of Gene Regulatory Networks
BH	Benjamini–Hochberg
Col4α1	Collagen 4 alpha chain 1
CPM	Counts per million
CRISPR	Clustered regularly interspaced short palindromic repeats
CSE	Cigarette smoke extract
CXCL8	Chemokine (C-X-C motif) ligand 8
DTT	Dithiothreitol
ECM	Extracellular matrix
FDR	False discovery rate
FEV1	Forced expiratory volume in 1 s
FEV1% Pred	Percentage of the patient FEV1 divided by the average FEV1 of the population
FN1	Fibronectin
GFP	Green fluorescent protein
gRNA	guide RNA
GSVA	Gene set variation analysis
IL-1β	Interleukin-1 beta
indel	Insertion or deletion of DNA bases
ITGA4	Integrin subunit alpha 4
ITGB8	Integrin subunit beta 8
LC-MS/MS	Liquid chromatography—tandem mass spectrometry
LFQ	Label-free quantification
MTT	3-4, 5-dimethylthiazol-2-(yl)-,5, diphenyltetrazolium
NH2OH	Hydroxylamine
OLiVIA	Effects Of Extra-fine ParticLe HFA-Beclomethasone Versus Coarse Particle Treatment In Smokers and Ex-smokers with Asthma
PAM	Protospacer adjacent motif
PMSF	Phenylmethylsulphonyl fluoride
pQTL	Protein quantitative trait loci
PVDF	Polyvinylidene difluoride
RP	Ribosomal protein
RPS4X	Ribosomal Protein S4 X-linked
RPS4Y1	Ribosomal Protein S4 Y-linked 1
rRNA	Ribosomal RNA
SDB-RPS	Styrene divinylbenzene-reverse phase sulfonated
SDS-PAGE	Sodium dodecyl sulfate-polyacrylamide gel electrophoresis
SPE	Solid phase extraction
STAT3	Signal transducer and activator of transcription 3
TEMED	N, N, N′, N′-tetramethyl ethylenediamine
TGF-β1	Transforming growth factor-beta
TNC	Tenascin C
TNFα	Tumour necrosis factor-alpha
UMAP	Uniform manifold approximation and projection for dimension reduction
X-chr	X chromosome
XCi	X-chromosome inactivation
Y-chr	Y chromosome