Table 2.

DNA binding activity of transcription factors in glial cells from PARP^+/+ and PARP^−/− mice

	PARP+/+		PARP−/−
	Basal LPS or TNF-α*		Basal LPS or TNF-α
Oct-1†	++	+++	+	+
AP-1	+	++	+	+
SP-1	++	++	+	+
Stat-1	++	+++	+	+
YY-1	++	+++	+	+

^*Glial cells were treated with 1 μg/ml of LPS or 1,000 units/ml of TNF-α for 30 min. 

^† Oligonucleotide sequences employed in the electrophoretic mobility-shift assays are described in Materials and Methods.