Why carry out this study?

Despite its importance, there is limited understanding of the impact of improved ON-time hours on advanced Parkinson’s disease (aPD) outcomes

This study evaluated the clinical, humanistic, and economic value of incremental hourly increases in ‘good ON-time’ (control without troublesome dyskinesia) for people with aPD

What was learned from the study?

Hourly increases in ‘good ON-time’ in people with aPD were associated with a lower likelihood of uncontrolled motor or non-motor symptoms, greater independence in daily activities, and reduced economic burden

Patients with aPD should be considered for treatments that maximize improvements of ‘good ON-time’, to ensure optimal benefit in disease outcomes