Table 4.

Mediation effect of PSV-L_PCL FC on PIGD score via MoCA score

Effect Type	Path	β	p value	95% CI
Direct effect	PSV-L_PCL FC → PIGD score	−4.90	0.049	(−9.80, −0.01)
Indirect effect	PSV-L_PCL FC → MoCA → PIGD score	−2.58	0.025	(−4.84, −0.32)
Total effect	PSV-L_PCL FC → PIGD score	−7.48	0.004	(−12.52, −2.45)
Path coefficient	MoCA → PIGD score	−0.20	<0.001	(−0.31, −0.10)
	PSV-L_PCL FC → MoCA	12.62	0.005	(3.78, 21.46)

The mediation model was adjusted for age, sex, education years, disease duration, LEDD, and UPDRS-III score. Bold indicates statistical significance (p < 0.05). 95% CI based on bootstrapping (5000 samples).

CI confidence interval, LEDD levodopa equivalent daily dose, L_PCL left paracentral lobule, MoCA Montreal Cognitive Assessment, PIGD postural instability and gait difficulty, PSV posterior superior vermis, UPDRS III Unified Parkinson’s Disease Rating Scale Part III.