Table 1.
Highest-ranked upregulated and downregulated proteins
| Number | Protein name | Gene | MW [kDa] | Sequence covered % | MASCOT score | 116/114 |
|---|---|---|---|---|---|---|
| Regulation (fold-change) | ||||||
| 1 | ARF GTPase-activating protein | GIT2 | 84.49 | 4.479578 | 93.143 | 0.166 |
| 2 | HLA class I histocompatibility antigen | HLA-B | 40.312 | 35.35912 | 478.75 | 0.167 |
| 3 | Testis-expressed sequence 30 protein | TEX30 | 25.568 | 18.06167 | 60.5876 | 0.171 |
| 4 | Cellular tumor antigen p53 | TP53 | 43.625 | 6.615776 | 54.37 | 0.182 |
| 5 | Protein CLN8 | CLN8 | 32.766 | 9.440559 | 81.86 | 0.184 |
| 6 | Cell cycle checkpoint protein RAD1 | RAD1 | 31.807 | 5.673759 | 38.308 | 0.185 |
| 7 | Prostaglandin E synthase | PTGES | 17.091 | 6.578947 | 44.95 | 0.192 |
| 8 | Transmembrane protein 201 | TMEM201 | 72.19 | 5.405405 | 119.41 | 0.235 |
| 9 | Metalloproteinase inhibitor 3 | TIMP3 | 24.129 | 13.74408 | 71.38 | 0.248 |
| 10 | Ceramide synthase 6 | CERS6 | 44.861 | 3.645833 | 33.13 | 0.261 |
| 11 | Tyrosine-protein kinase Yes | YES1 | 60.763 | 25.41436 | 298.163 | 0.263 |
| 12 | Histone H3 | HIST2H3A | 15.394 | 64.70588 | 723.664 | 3.584 |
| 13 | Annexin A8-like protein 1 | ANXA8L1 | 36.856 | 44.64832 | 643.28 | 3.626 |
| 14 | Serpin B5 | SERPINB5 | 42.073 | 19.2 | 160.987 | 3.636 |
| 15 | Beta-taxilin | TXLNB | 76.472 | 2.192982 | 29.71 | 3.785 |
| 16 | Cathepsin S | CTSS | 37.471 | 12.99094 | 65.296 | 3.945 |
| 17 | Metallothionein-1E | MT1E | 6.009 | 67.21311 | 548.883 | 3.955 |
| 18 | 14-3-3 protein sigma | SFN | 27.757 | 71.37097 | 1647.65 | 4.508 |
| 19 | Protein S100-A2 | S100A2 | 11.109 | 27.55102 | 219.182 | 5.388 |
| 20 | Copine-9 | CPNE9 | 61.825 | 3.074141 | 72.459 | 5.407 |
| 21 | Stonin-2 | STON2 | 101.102 | 0.994475 | 38.172 | 6.008 |
| 22 | Fatty acid-binding protein | FABP4 | 15.155 | 72.59259 | 87.72 | 7.37 |
| 23 | Peptidase M20 domain-containing protein 2 | PM20D2 | 47.746 | 2.522936 | 37.55 | 9.421 |