Table 6.
Multivariate cox regression analysis of independent factors associated with recurrence-free survival
| Variable | Beta | Std. Error | P Value | HR | Lower | Upper |
|---|---|---|---|---|---|---|
| Age | ||||||
| ≥ 60 | ||||||
| < 60 | -0.491 | 0.185 | 0.008 | 0.612 | 0.426 | 0.879 |
| T Stage | ||||||
| T1 | ||||||
| T2 | 0.339 | 0.208 | 0.103 | 1.404 | 0.934 | 2.111 |
| T3 | 0.736 | 0.221 | 0.001 | 2.087 | 1.353 | 3.221 |
| Lymph Node Metastasis | ||||||
| Yes | ||||||
| No | -0.784 | 0.188 | < 0.001 | 0.457 | 0.316 | 0.66 |
| Degree of Differentiation | ||||||
| Poorly Differentiated | ||||||
| Moderately + Well Differentiated | -0.553 | 0.166 | 0.001 | 0.575 | 0.416 | 0.796 |
| Postoperative Chemotherapy | ||||||
| Yes | ||||||
| No | 1.105 | 0.215 | < 0.001 | 3.019 | 1.981 | 4.599 |
| IL-6 | 0.146 | 0.018 | < 0.001 | 1.158 | 1.118 | 1.199 |
| IL-8 | 0.048 | 0.01 | < 0.001 | 1.049 | 1.028 | 1.07 |
| PNI | -0.012 | 0.002 | < 0.001 | 0.988 | 0.984 | 0.991 |
| NLR | 0.035 | 0.039 | 0.362 | 1.036 | 0.96 | 1.118 |
| PLR | 0.004 | 0.001 | < 0.001 | 1.004 | 1.002 | 1.006 |
Note: HR, Hazard Ratio; PNI, Prognostic Nutritional Index; NLR, Neutrophil-to-Lymphocyte Ratio; PLR, Platelet-to-Lymphocyte Ratio; IL-6, Interleukin-6; IL-8, Interleukin-8; T Stage, T Stage.