Table 8.
Multivariate analysis of factors affecting survival outcomes in osteosarcoma patients
| Influencing factors | Coefficient | Std Error | Wald Stat | P | OR | OR CI Lower | OR CI Upper |
|---|---|---|---|---|---|---|---|
| Pathologic fracture at diagnosis (Yes/No) | -1.433 | 0.622 | -2.302 | 0.021 | 0.239 | 0.070 | 0.808 |
| Lung metastases (Yes/No) | -1.674 | 0.646 | -2.593 | 0.010 | 0.187 | 0.053 | 0.664 |
| Completed treatment (Yes/No) | 1.912 | 0.847 | 2.258 | 0.024 | 6.768 | 1.287 | 35.591 |
| Chemotherapy response (Greater than 90%/Less than 90%) | 2.597 | 0.887 | 2.927 | 0.003 | 13.421 | 2.358 | 76.393 |
| LDH level (Normal/High) | -1.551 | 0.616 | -2.520 | 0.012 | 0.212 | 0.063 | 0.709 |
| Radiation (Yes/No) | -1.784 | 1.028 | -1.735 | 0.083 | 0.168 | 0.022 | 1.260 |
| Tumor volume (mL) (≤ 150/> 150) | 1.131 | 0.623 | 1.817 | 0.069 | 3.100 | 0.915 | 10.507 |
| Pain symptoms (No/Yes) | -1.894 | 0.724 | -2.618 | 0.009 | 0.150 | 0.036 | 0.621 |
| Histological response (Good/Poor) | 1.485 | 0.650 | 2.284 | 0.022 | 4.416 | 1.235 | 15.793 |
OR: Odds Ratio; CI: Confidence Interval; LDH level: Lactate Dehydrogenase.