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. 2025 Jul 13;15:25296. doi: 10.1038/s41598-025-09678-5

Table 4.

Subgroup analysis for remnant cholesterol and incident hypertension.

Subgroup Case/total < 31, mg/dl 31–46, mg/dl ≥ 46, mg/dl P for interaction
Ref. HR (95% CI), P-value HR (95% CI), P-value
Age group 0.673
< 60 years 472/1,843 Ref. 0.93 (95% CI:0.72, 1.19), 0.549 1.26 (95% CI:0.95, 1.68), 0.112
≥ 60 years 367/1,201 Ref. 1.08 (95% CI:0.81, 1.44), 0.610 1.29 (95% CI:0.89, 1.85), 0.177
Gender 0.770
Female 417/1,618 Ref. 1.04 (95% CI:0.81, 1.33), 0.765 1.29 (95% CI:0.94, 1.77), 0.118
Male 421/1,426 Ref. 0.95 (95% CI:0.70, 1.27), 0.709 1.39 (95% CI:1.02, 1.90), 0.036
Diabetes 0.238
None 722/2,727 Ref. 1.04 (95% CI:0.85, 1.28), 0.702 1.32 (95% CI:1.03, 1.68), 0.029
Yes 117/317 Ref. 0.75 (95% CI:0.47, 1.20), 0.232 1.21 (95% CI:0.72, 2.05), 0.468
Heart disease 0.829
None 773/2,787 Ref. 0.99 (95% CI:0.82, 1.21), 0.959 1.32 (95% CI:1.04, 1.66), 0.020
Yes 66/257 Ref. 1.05 (95% CI:0.55, 2.00), 0.884 0.79 (95% CI:0.34, 1.87), 0.595
Chronic kidney disease 0.146
None 801/2,855 0.98 (95% CI:0.81, 1.19), 0.825 1.25 (95% CI:0.99, 1.57), 0.057
Yes 38/189 0.82 (95% CI:0.18, 3.70), 0.792 1.91 (95% CI:0.60, 6.11), 0.275
HR = hazard risk; 95% CI = 95% confidence interval; Ref. = Reference