Table 2. Comparisons of changes in each variable from baseline at 12-month visit in the TRT and control groups.
| Variable | TRT group (n=88) | Control group (n=98) | p-value |
|---|---|---|---|
| Weist circumference (cm) | -0.5±3.1 | 1.0±8.4 | 0.00248 |
| BMI (kg/m2) | 0.1±0.8 | 0.1±1.0 | 0.443 |
| Fat volume (kg) | -1.0±4.3 | 0.5±4.0 | 0.00812 |
| Platelet (1,000/µL) | 1.5±31.6 | -6.2±30.8 | 0.0478 |
| AST (IU/L) | 0.5±8.7 | 0.9±8.9 | 0.386 |
| ALT (IU/L) | 0.8±8.4 | 23.8±13.9 | 0.161 |
| FBS (mg/dL) | 0.8±45.0 | 8.5±42.9 | 0.121 |
| HbA1c (%) | 0.0±0.5 | 0.0±0.4 | 0.308 |
| T-Chol (mg/dL) | -1.3±22.3 | -3.0±26.4 | 0.324 |
| TG (mg/dL) | -8.4±73.0 | 4.9±42.1 | 0.0639 |
| HDL-Chol (mg/dL) | -1.7±7.8 | -1.4±7.2 | 0.381 |
| FIB-4 index | -0.02± 0.36 | 0.06±0.07 | 0.0599 |
Values are presented as mean±standard deviation.
TRT: testosterone replacement therapy, BMI: body mass index, AST: aspartate aminotransferase, ALT: alanine transaminase, FBS: fasting blood sugar, HbA1c: hemoglobin A1c, T-Chol: total cholesterol, TG: triglyceride, HDL-Chol: high-density lipoprotein cholesterol, FIB-4: Fibrosis-4.