Table 4. Comparisons of changes in each parameter from baseline among the patients with lower FIB-4 index (<1.30) at baseline in TRT and control groups.
| Variable | TRT group (n=29) | Control group (n=31) | p-value |
|---|---|---|---|
| Weist circumference (cm) | 0.3±2.8 | 1.8±3.9 | 0.0475 |
| BMI (kg/m2) | 0.1±0.7 | 0.3±1.0 | 0.126 |
| Fat volume (kg) | -0.4±2.7 | 0.9±4.6 | 0.0264 |
| Platelet (1,000/µL) | -8.0±32.8 | -18.6±41.1 | 0.138 |
| AST (IU/L) | 3.2±11.2 | 4.2±7.4 | 0.344 |
| ALT (IU/L) | 1.6±7.3 | 5.8±12.9 | 0.0619 |
| FBS (mg/dL) | 4.7±48.4 | 3.9±45.5 | 0.475 |
| HbA1c (%) | 0.0±0.5 | 0.0±0.4 | 0.198 |
| T-Chol (mg/dL) | 2.8±20.1 | -5.2±35.0 | 0.154 |
| TG (mg/dL) | 2.8±107.6 | 8.9±46.8 | 0.386 |
| HDL-Chol (mg/dL) | -2.2±8.3 | -1.0±6.8 | 0.263 |
| FIB-4 index | 0.09±0.21 | 0.20±0.27 | 0.095 |
Values are presented as mean±standard deviation.
TRT: testosterone replacement therapy, BMI: body mass index, AST: aspartate aminotransferase, ALT: alanine transaminase, FBS: fasting blood sugar, HbA1c: hemoglobin A1c, T-Chol: total cholesterol, TG: triglyceride, HDL-Chol: high-density lipoprotein cholesterol, FIB-4: Fibrosis-4.