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. 2025 Jul 13;22:159. doi: 10.1186/s12984-025-01694-w

Table 2.

Patients’ classification according to their disease

Grouped by disease
Missing CANOMAD CIDP Hereditary neuropathy IgM-MGUS AN Controls p value
N (%) 3 (3.8) 37 (46.8) 11 (13.9) 21 (26.5) 7 (8.9) 50
Age (years), mean (SD) 0 72.2 (9.4) 59.5 (10.4) 54.5 (15.3) 67.1 (9.3) 57.7 (21.4) 59.9 (9.4) 0.015
Sex, male (%) 2 (66.7) 20 (54.1) 4 (36.4) 19 (90.5) 6 (85.7) 17 (34.0)
2 MWT distance (m), mean (SD) 0 109.3 (11.4) 127.1 (44.3) 117.5 (43.6) 147.0 (27.5) 127.7 (42.8) 198.0 (35.3)  < 0.001
Vigorimeter, mean (SD)
 Left 0 53.3 (25.2) 62.8 (25.6) 65.7 (25.6) 80.8 (26.4) 71.4 (20.6) NA
 Right 0 46.0 (24.2) 61.4 (22.8) 62.2 (24.2) 79.4 (22.8) 70.6 (20.3) NA
MRCss total, mean (SD) 0 58.3 (1.5) 57.5 (3.0) 56.1 (3.9) 59.0 (1.8) 56.7 (3.7) NA NA
INCAT total, mean (SD) 1 2.3 (1.4) 2.4 (1.4) 2.4 (1.6) 1.4 (1.2) 1.9 (1.5) NA NA
iRODS total, mean (SD) 8 35.0 (4.2) 35.1 (7.7) 35.8 (9.3) 40.6 (5.7) 40.4 (8.3) NA NA

Number, mean, standard deviation (sd) of patients included of each pathology according to age and sex. Mean and sd results of 2-min-walking-test (2MWT), grip strength using vigorimeter, Medical Research Council sum score (MRCss), Inflammatory Neuropathy Cause and Treatment (INCAT), Inflammatory Rasch-built Overall Disability Scale (iRODS). NA refers to not applicable in that specific variable. Chi-quadrat test used for study the differences between sex and ANOVA test used to analyze the differences between controls and patients in 2MWT

CANOMAD chronic ataxic neuropathy, ophthalmoplegia, immunoglobulin M [IgM] paraprotein, cold agglutinins, and disialosyl antibodies; CIDP chronic inflammatory demyelinating polyneuropathy; IgM-MGUS monoclonal gammopathy of undetermined significance associated with IgM; AN autoimmune nodopathy