TABLE 4.
CRISPR/Cas applications in tuber crop improvement*.
| Crop | Edited gene | Improved trait | References |
|---|---|---|---|
| Ipomoea batatas (sweetpotato) | IbGBSSI, IbSBEII | Improved starch properties via amylose modification | Wang et al. (2019a) |
| Manihot esculenta (cassava) | MeSSIII-1 | Increased amylose and resistant starch content in the storage roots | Lu et al. (2025) |
| CYP79D1, CYP79D2 | Reduced cyanide levels for enhanced food safety | Gomez et al. (2023) | |
| MeSWEET10a | Increased tolerance to bacterial blight | Elliott et al. (2023) | |
| MeCYP79D1 | Reduced linamarin and cyanide content for enhanced food safety | Juma et al. (2022) | |
| nCBP-1, nCBP-2 | Improved tolerance to brown streak disease with reduced root necrosis and virus load | Gomez et al. (2019) | |
| Solanum tuberosum (potato) | InvVac, PPO2 | Improved cold storage and bruising resistance via suppression of cold-induced sweetening and enzymatic browning | Massa et al. (2025) |
| StPM1 | Improved resistance to Phytophthora infestans | Bi et al. (2024) | |
| Parakletos | Broad-spectrum resistance to biotic and abiotic stresses with increased field yield | Zahid et al. (2024) | |
| StDND1, StCHL1, StDMR6-1 | Enhanced resistance to late blight | Kieu et al. (2021) | |
| Coilin | Increased resistance to potato virus Y and stress tolerance | Makhotenko et al. (2019) | |
| StPPO2 | Reduced enzymatic browning in tubers | González et al. (2020) | |
| S-RN | Self-incompatibility breakdown for hybrid breeding | Enciso-Rodriguez et al. (2019) |
* Note: Only peer-reviewed scientific studies published between 2019 and 2025 are included.