Figure A2.
Three chromosomes typed for four marker loci, illustrating the parameters used in calculation of the haplotype-transition probabilities. The markers are represented as rectangles, and the mutation is represented as an ellipse. The marker-allele designations are shown above each chromosome, and the marker-locus labels are shown below each chromosome. All markers are biallelic, with “0” denoting the ancestral allele. The parameter K is the marker immediately to the right of the mutation; AR is the locus nearest to M, on the right, with a nonarrested allele; and ALis the nearest such locus on the left. In panel a, AR=3; in panel b, AR=3 and AL=0; in panel c, AR=4 and AL=1.