Figure 1.
Cosegregation analysis of CRB1 mutations in (A) one family with LCA and (B) five families with RP and Coats-like exudates. A question mark (?) denotes the unidentified second allele; an asterisk (*) denotes patients with RP who have developed the Coats-like complication. Arrows indicate probands. IVS8 denotes the splice-site mutation of exon 8, 2978+5G→A.