Table 1.
Expected and observed frequency of genotypes of 308 F2 mice obtained from brother-sister breeding of TSK/+, IL-4+/− F1 mice
| Genotype | Expected
|
Observed
|
FX† | ||
|---|---|---|---|---|---|
| % | no.* | % | no.* | ||
| TSK/TSK IL-4+/+ | 6.3 | 19 | 0 | 0 | 0 |
| TSK/TSK IL-4+/− | 12.5 | 38 | 3.6 | 11 | 0.29 |
| TSK/TSK IL-4−/− | 6.3 | 19 | 2.9 | 9 | 0.47 |
| TSK/+ IL-4+/+ | 12.5 | 38 | 18.5 | 57 | |
| TSK/+ IL-4+/− | 25 | 77 | 28.9 | 89 | |
| TSK/+ IL-4−/− | 12.5 | 38 | 16.5 | 51 | |
| +/+ IL-4+/+ | 6.3 | 19 | 6.8 | 21 | |
| +/+ IL-4+/− | 12.5 | 38 | 14.2 | 44 | |
| +/+ IL-4−/− | 6.3 | 19 | 8.4 | 26 | |
*
Number of F2 mice genotyped.
†
FX is calculated as the ratio of the number of mice observed/number of mice expected.