Figure 1.

Electropherograms, showing germline SDHB mutations (arrowheads), and simplified pedigrees for families K1–K3 (A) and family K4 (B). The affected codon and the amino acids are depicted below the electropherograms. In pedigrees, symbols with horizontal bars indicate pheochromocytoma (intra- or extra-adrenal), symbols with vertical bars indicate cervical paraganglioma, and symbols with checkered pattern indicate both pheochromocytoma and paraganglioma.