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. 2001 Jun 14;69(1):75–87. doi: 10.1086/321285

Figure 3.

Figure 3

A, Graph of results of electrophoresis of the allele-specific PCR of the index patient and the mosaic individual of family LA14. The upper four traces show the strength of the mutated allele in the index patient for different dilutions of the allele-specific PCR product. The mutation can be clearly detected in the trace of the 1:200 dilution (trace 3). The mosaic individual (trace 5) showed a strength of the allele-specific PCR product comparable to a 1:20 dilution (trace 2), thus corresponding to a proportion of 5% of the mutated allele. The last trace represents a negative control. B, Nucleotide sequence after mutation enrichment. Results clearly indicate the presence of the mutated allele.