Table 1.
Results for Allele Frequencies from Control Population |
Results for Allele Frequencies from Pedigree |
|||
Chromosome and Marker | MLS (θa) | Diagnosis | MLS (θa) | Diagnosis |
2: | ||||
D2S337 | 2.60 (.15) | Scz | .00 (.35) | Scz |
D2S151 | 1.72 (.15) | Scz | .95 (.15) | Scz |
D2S125 | 2.14 (.20) | Brd1 | .34 (.30) | Brd2 |
3: | ||||
D3S1297 | 1.72 (.15) | Brd1 | .01 (.30) | Scz |
D3S1304 | 2.72 (.10) | Brd1 | .57 (.20) | Brd2 |
D3S1263 | 3.30 (.15) | Brd2 | .30 (.25) | SAD |
D3S1566 | 1.76 (.10) | Brd2 | .53 (.15) | Brd1 |
D3S1580 | 1.55 (.15) | Scz | .18 (.30) | Scz |
5: | ||||
D5S419 | 2.02 (.20) | Brd1 | .47 (.20) | Brd2 |
D5S644 | 1.82 (.15) | Scz | .49 (.25) | SAD |
D5S433 | 1.59 (.20) | Brd2 | .08 (.30) | Scz |
6: | ||||
D6S344 | 3.60 (.05) | Scz | −.03 (.40) | Scz |
D6S264 | 3.45 (.00) | Brd1 | 2.59 (.00) | Brd1 |
7: | ||||
D7S636 | 2.00 (.10) | Scz | .00 (.20) | Scz |
8: | ||||
D8S550 | 2.90 (.15) | Scz | .70 (.15) | Scz |
9: | ||||
D9S157 | 1.72 (.05) | Scz | 1.47 (.05) | Scz |
D9S175 | 2.00 (.15) | SAD | .00 (.20) | SAD |
D9S299 | 2.01 (.05) | Brd2 | 1.11 (.10) | Brd2 |
10: | ||||
D10S189 | 1.94 (.10) | Brd2 | .38 (.20) | Brd2 |
11: | ||||
D11S1324 | 1.74 (.20) | Brd2 | −.03 (.40) | Scz |
13: | ||||
D13S283 | 1.66 (.15) | Scz | .65 (.15) | Scz |
D13S152 | 1.58 (.20) | Brd2 | .04 (.35) | Brd1 |
D13S173 | 1.53 (.10) | SAD | .53 (.15) | SAD |
14: | ||||
D14S258 | 1.60 (.15) | Brd1 | .00 (.20) | Brd1 |
16: | ||||
D16S401 | 2.52 (.15) | SAD | .23 (.30) | Scz |
20: | ||||
D20S118 | 3.57 (.20) | Brd2 | −.12 (.40) | Scz |
D20S178 | 2.70 (.15) | Brd2 | .10 (.25) | Brd1 |
D20S100 | 1.76 (.10) | Scz | 1.37 (.10) | Scz |
D20S173 | 2.39 (.15) | SAD | .05 (.35) | Scz |
21: | ||||
D21S266 | 1.61 (.15) | Scz | .27 (.25) | Scz |
22: | ||||
D22S280 | 1.61 (.15) | Brd2 | .09 (.30) | Brd2 |
Note.— The MLS values for marker D6S264, which reached suggestive levels of significance in both the Swedish control population and the pedigree, are underlined.
Recombination fraction.