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Inheritance Model for an Epistatic Two-Locus Trait[Note]
|
Locus 2 |
|||
| Locus 1 | BB | Bb | bb |
| AA | 0 | 0 | 0 |
| Aa | 0 | 0 | 1 |
| aa | 1 | 1 | 1 |
Note.— Locus 1 is recessive, given genotypes BB and Bb at locus 2, and is dominant, given genotype bb. Disease-allele frequencies are set at p(a)=.01 and p(b)=.02.
