Table 3.
Detection of a Weak Locus with an Epistatic Interaction[Note]
|
Power at Lod Score Cut-Off |
Pointwise Type I Error at Cut-Off |
|||||||
| Model | .59 (1.13) | .92 (1.50) | 1.18 (1.80) | 1.44 (2.09) | .59 (1.13) | .92 (1.50) | 1.18 (1.80) | 1.44 (2.09) |
| Ising | .377 | .263 | .190 | .138 | .030 | .013 | .008 | .006 |
| χ2 (0 and 1 sharers at locus 1) | .326 | .189 | .113 | .064 | .044 | .018 | .008 | .004 |
| χ2/Allegro (single-locus) | .286 | .176 | .119 | .088 | .049 | .020 | .009 | .005 |
Note.— The cut-off levels in parenthesis refer to the 2-df LR test in the Ising model with epistatic interaction. The P values corresponding to the LODs shown are .05, .02, .01, and .005, respectively.