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. 2025 Jun 27;16(3):1220–1232. doi: 10.21037/jgo-2024-1022

Table 2. Univariate and multivariate cox regression analyses of factors affecting overall patient survival.

Variable Univariate Multivariate
P HR 95% CI P HR 95% CI
Chemotherapy 0.29 1.239 0.835, 1.838 0.20 1.368 0.848, 2.204
Gender, vs. female
   Male 0.54 1.13 0.763, 1.673 0.90 1.031 0.630, 1.687
Age (years)
   ≤50 0.02 0.03
   51–74 0.03 2.277 1.095, 4.736 0.01 2.974 1.243, 7.118
   ≥75 0.006 3.366 1.415, 8.005 0.009 4.097 1.411, 11.892
Race
   White 0.48
   Black 0.99 0.997 0.538, 1.85
   Hispanic 0.59 0.866 0.512, 1.463
   Asian 0.13 0.685 0.423, 1.11
Marriage
   Unmarried 0.22
   Married 0.56 1.187 0.672, 2.097
   Divorced/separated/widowed 0.11 1.755 0.879, 3.501
T stage
   T1 <0.001 0.001
   T2 0.001 2.236 1.375, 3.635 0.010 1.972 1.179, 3.297
   T3 <0.001 3.563 2.036, 6.234 0.001 3.010 1.586, 5.713
   T4 <0.001 3.662 1.871, 7.168 0.001 3.628 1.659, 7.934
N stage, vs. N0
   N1 0.02 2.25 1.127, 4.489 0.18 1.784 0.772, 4.120
M stage, vs. M0
   M1 0.059 2.115 0.971, 4.606 0.94 1.041 0.386, 2.808
Household income (dollar)
   <55,000 0.46
   55,000–75,000 0.65 0.881 0.513, 1.513
   >75,000 0.26 0.733 0.426, 1.259
Radiotherapy 0.18 0.047 0.001, 4.119 0.97 <0.001 <0.001, >999

CI, confidence interval; HR, hazard ratio; M, metastasis; N, node; T, tumor.