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. 2025 Jun 27;16(3):1220–1232. doi: 10.21037/jgo-2024-1022

Table 3. Univariate and multivariate cox regression analyses of factors affecting overall patient survival of 3-year.

Variable Univariate Multivariate
P HR 95% CI P HR 95% CI
Chemotherapy 0.07 1.473 0.967, 2.246 0.12 1.511 0.903, 2.528
Gender, vs. female
   Male 0.14 1.415 0.895, 2.239 0.26 1.394 0.778, 2.498
Age (years)
   ≤50 0.27 0.38
   51–74 0.20 1.658 0.763, 3.601 0.22 1.725 0.716, 4.152
   ≥75 0.11 2.14 0.853, 5.371 0.18 2.127 0.709, 6.384
Race
   White 0.81
   Black 0.79 0.909 0.447, 1.848
   Hispanic 0.92 1.028 0.585, 1.805
   Asian 0.37 0.783 0.462, 1.329
Marriage
   Unmarried 0.60
   Married 0.71 1.125 0.607, 2.085
   Divorced/separated/widowed 0.34 1.451 0.671, 3.138
T stage
   T1 <0.001 0.004
   T2 0.001 2.597 1.489, 4.532 0.01 2.117 1.174, 3.819
   T3 <0.001 3.487 1.846, 6.588 0.002 3.173 1.528, 6.587
   T4 <0.001 4.157 2.006, 8.614 0.007 3.262 1.389, 7.662
N stage, vs. N0
   N1 0.02 2.361 1.132, 4.928 0.22 1.738 0.715, 4.228
M stage, vs. M0
   M1 0.17 1.797 0.78, 4.141 0.57 0.735 0.257, 2.106
Household income (dollar)
   <55,000 0.73
   55,000–75,000 0.99 0.996 0.533, 1.863
   >75,000 0.60 0.847 0.454, 1.58
Radiotherapy 0.28 0.048 <0.001, 12.304 0.97 <0.001 <0.001, >999

CI, confidence interval; HR, hazard ratio; M, metastasis; N, node; T, tumor.