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Comparison of muscle α-skeletal-actin protein sequences in various species and in the five mutated residues in the patients. All mutated residues in α-skeletal actin are highly conserved across the species shown. An asterisk (*) denotes conserved amino acid, and a dash (–) denotes a deleted amino acid. The amino acid numbering nomenclature corresponds to that of the human muscle α-skeletal-actin protein sequence.
