Table 3.
With PSD | Total | |
Families in Class I |
||
175.4 cM; 2.99 HLOD; α = .69 | 181.1 cM; 1.97 HLOD; α = .50 | |
Dominant | 174.0 cM; 1.52 LOD | 183.3 cM; −3.49 LOD; |
174.4 cM; 2.71 HLOD; α = .50 | 174.0 cM; 1.47 HLOD; α = .27 | |
Recessive | 174.4 cM; −1.88 LOD; | 172.6 cM; −13.21 LOD; |
NPL | 176.8 cM; Z-score = 3.32; P = 3.8 × 10−4 | 176.8 cM; Z-score = 2.47; P = 6.2 × 10−3 |
Families in Classes I and II |
||
179.0 cM; 2.62 HLOD; α = .61 | 183.3 cM; 1.96 HLOD; α = .48 | |
Dominant | 181.2 cM; −.30 LOD | 183.3 cM; −4.54 LOD |
175.4 cM; 2.46 HLOD; α = .42 | 174.0 cM; 1.38 HLOD; α = .24 | |
Recessive | 174.0 cM; −5.06 LOD; | 174.0 cM; −18.05 LOD; |
NPL | 176.8 cM; Z-score = 3.17; P = 7.1 × 10−4 | 176.8 cM; Z-score = 2.39; P = 7.8 × 10−3 |
Note.— Multipoint LOD and HLOD scores were calculated under dominant or recessive models, as detailed in the legend to figure 1. The peak score is indicated, along with its position and, for HLOD, the estimated fraction of families with linkage (α). Multipoint NPL scores are also indicated, along with the position of the peak, and associated P values.