Fig. 1.

(a-i) The schematic of the sheath-assisted and pneumatic-induced nano-sieve device presenting an overview of channel configuration. (a-ii) The local region of MRSA–bead interface. (a-iii) MRSA physically concentrated by stacked beads with diameters of 10 μm and 1 μm. (b) Fabrication procedure of the device by plasma bonding the PDMS pneumatic chamber, PDMS thin film, and channel-patterned glass substrate. (c) The optical picture showing the experimental device with low and high magnifications.