Table 1.

Summary of CNPs Detected by Array CGH^[Note]

				No. of CNPs
Ethnic Group	No. of SubjectsAnalyzed	Gains	Losses	Showing BothGain and Loss	Detected inPresent Study	Detected bySebat et al. (2004)	Detected byIafrate et al. (2004)	Novel
American Indians	7	9	22	13	44	18	9	22
Sub-Saharan Africans	16	27	31	17	75	24	14	43
Whites	12	17	22	12	51	16	13	25
Asians	12	26	27	15	68	21	14	37
Nonredundant total	47	52	50	17	119	22	21	73

Note.— CNPs were scored as either increased or decreased log₂ ratios (i.e., gains or losses), relative to the reference DNA. In total, 46 (39%) of 119 of the CNPs we identified have been reported previously, which thus validates the ability of our array to detect known copy-number variations. In our sample population, we identified 22 (71%) of the 31 CNPs detected by Sebat et al. (2004) and 22 (39%) of the 57 CNPs detected by Iafrate et al. (2004) that were represented on the SD microarray.