Table 2.
Best Gene-Gene Effect Models Identified by EMDR for GABAR Subunit Genes on Chromosome 4
|
Nonfixed P Valuea |
|||||
| Geneand Marker | Marker Number | Location | Best Model | χ2 | Misclassification |
| GABRG1: | |||||
| RS1497571 | 1 | 65.47 | 9 | .06 | .038 |
| RS2350439 | 2 | 65.49 | 9, 13 | .004 | .002b |
| GABRA2: | 2, 9, 15 | .016 | .03 | ||
| RS279858 | 3 | 65.66 | 2, 7, 9, 15 | .16 | .33 |
| RS279844 | 4 | 65.66 | |||
| HCV8262290 | 5 | 65.67 | |||
| RS4695152 | 6 | 65.68 | |||
| HCV8262334 | 7 | 65.68 | |||
| GABRA4: | |||||
| HCV1592545 | 8 | 65.85 | |||
| RS1912960 | 9 | 65.86 | |||
| RS2280073 | 10 | 65.86 | |||
| RS10517174 | 11 | 65.87 | |||
| RS3792211 | 12 | 65.87 | |||
| GABRB1: | |||||
| RS2351299 | 13 | 65.92 | |||
| RS1372496 | 14 | 65.94 | |||
| RS3114084 | 15 | 65.95 | |||
| HCV11353524 | 16 | 65.97 | |||
| HCV2119841 | 17 | 65.99 | |||
| RS6289 | 18 | 66.00 | |||
| RS6290 | 19 | 66.00 | |||
a
Empirical P value derived from nonfixed permutation test by use of χ2 or the misclassification rate as the test statistic in EMDR.
b
The locus with the lowest P value (in bold italics) was selected as the one for the final cross-chromosome model.