Table 4.
Best Gene-Gene Effect Models Identified by EMDR for GABAR Subunit Genes on Chromosome 6
|
Nonfixed P Valuea |
|||||
| Genesand Marker | Marker Number | Location | Best Model | χ2 | Misclassification |
| GABRR1: | |||||
| RS404943 | 1 | 94.926 | 8 | .644 | .587 |
| RS407206 | 2 | 94.935 | 5, 11 | .579 | .452 |
| RS423463 | 3 | 94.946 | 2, 8, 10 | .398 | .246b |
| RS3777530 | 4 | 94.975 | 7, 8, 10, 11 | .645 | .665 |
| RS2297389 | 5 | 94.991 | |||
| RS881293 | 6 | 94.998 | |||
| RS6902106 | 7 | 95.019 | |||
| GABRR2: | |||||
| RS282117 | 8 | 95.171 | |||
| HCV9866022 | 9 | 95.208 | |||
| RS2148174 | 10 | 95.238 | |||
| HCV9865968 | 11 | 95.277 | |||
a
Empirical P value derived from nonfixed permutation test by use of χ2 or the misclassification rate as the test statistic in EMDR.
b
The locus with the lowest P value (in bold italics) was selected as the one for the final cross-chromosome model.