Table 5.
Best Gene-Gene Effect Models Identified by EMDR for GABAR Subunit Genes on Chromosome 15
|
Nonfixed P Valuea |
|||||
| Geneand Marker | Marker Number | Location | Best Model | χ2 | Misclassification |
| GABRB3: | |||||
| RS2081648 | 1 | 11.07 | 10 | .219b | .706 |
| RS1426217 | 2 | 11.08 | 5, 10 | .494 | .56 |
| RS754185 | 3 | 11.23 | 4, 10, 13 | .843 | .85 |
| HCV8865209 | 4 | 11.33 | 4, 5, 10, 13 | .623 | .875 |
| RS2059574 | 5 | 11.54 | |||
| GABRA5: | |||||
| HCV42974 | 6 | 12.06 | |||
| RS140681 | 7 | 12.12 | |||
| RS140683 | 8 | 12.14 | |||
| GABRG3: | |||||
| HCV2078506 | 9 | 12.38 | |||
| RS208129 | 10 | 12.81 | |||
| RS897173 | 11 | 12.94 | |||
| HCV428306 | 12 | 14.46 | |||
| RS140679 | 13 | 14.66 | |||
a
Empirical P value derived from nonfixed permutation test by use of χ2 or the misclassification rate as the test statistic in EMDR.
b
The locus with the lowest P value (in bold italics) was selected as the one for the final cross-chromosome model.