. 2005 Jul 26;77(3):389–407. doi: 10.1086/444437

Table 8.

ORs, ARs, and Simulated P Values from χ² Test with 10,000 Replicates^[Note]

		Dominant([RR+RN] vs. NN)				Heterozygotes(RR vs. NN)		Recessive(RR vs. [RN+NN])				Homozygotes(RR vs. NN)
SNP (Allele)	Gene	OR	95% CI	AR	P	OR	AR	OR	95% CI	AR	P	OR	AR
rs6658788 (2)		.83	.57–1.22	−14.04	.3909	1.09	2.69	1.01	.68–1.5	.21	1	.88	−5.92
rs1538687 (2)		*.68*	.49–.95	*−19.38*	.023	.5	*−11.74*	*.42*	.23–.78	*−6.52*	.0068	*.38*	*−12.42*
rs1416962 (2)		.84	.6–1.18	−10.02	.3418	.89	−2.57	.82	.49–1.38	−2.31	.5002	.77	−5.74
rs946755 (2)		.8	.57–1.13	−12.52	.232	1	.04	.9	.53–1.52	−1.24	.7816	.81	−4.34
rs6428352 (2)		…	…	…	…	…	…	…	…	…	…	…	…
rs800292 (1)	CFH	.43	.3–.62	−30.01	<.0001	.48	−23.85	.15	.05–.45	−4.98	.0001	.12	−8.19
*rs1061170* (2)	CFH	5.29	3.35–8.35	68.2	<.0001	*2.66*	*28.55*	4.57	2.48–8.42	30.06	<.0001	10.05	63.72
*rs10922093* (1)	CFH	*.59*	.39–.88	*−25.61*	.0111	*.63*	*−19.65*	.5	.24–1.04	−4.98	.0736	*.41*	*−10.14*
rs70620 (1)	CFH	.83	.57–1.19	−5.64	.3366	.85	−4.29	.67	.27–1.68	−1.3	.4525	.64	−1.93
rs1853883 (2)		2.67	1.78–4.01	54.41	<.0001	*1.65*	*19.21*	2.08	1.43–3.02	22.06	.0003	3.55	55.04
rs1360558 (1)		1.16	.82–1.65	9.12	.414	1.1	5.39	1.25	.8–1.96	3.94	.3774	1.32	9.01
rs955927 (2)		1.13	.79–1.6	7.5	.5303	1.28	6.35	1.31	.83–2.08	4.53	.2588	1.36	9.38
rs4350226 (2)		*.51*	.32–.81	*−9.68*	.0038	.27	−4.76	.16	.01–1.74	−.95	.142	.14	−1.16
rs4752266 (2)	GRK5	.88	.62–1.23	−5.57	.4325	*3.27*	*10.68*	*2.81*	.98–8.04	*3.89*	.0457	2.56	5.51
rs915394 (2)	GRK5	1.28	.9–1.82	8.91	.1543	1.35	2.73	1.56	.58–4.14	1.53	.3892	1.68	2.72
rs1268947 (2)	GRK5	1.05	.7–1.57	1.06	.841	1.24	1.82	1.27	.35–4.55	.45	.7761	1.28	.58
rs1537576 (2)	GRK5	*1.59*	1.11–2.29	*27.95*	.0109	.89	−3.74	1.08	.71–1.62	1.59	.7579	1.47	15.14
rs2039488 (2)		.7	.45–1.07	−6.5	.1067	.23	−11.98	*.19*	.04–.79	*−2.33*	.0242	*.18*	*−2.85*
rs1467813 (1)	RGS10	.96	.69–1.35	−1.84	.8645	1.01	.42	.77	.42–1.38	−2.27	.4265	.77	−3.76
rs927427 (1)		1.09	.74–1.62	6.57	.6172	.94	−4.66	*1.67*	1.09–2.56	*10.73*	.0201	1.6	19.91
rs4146894 (1)	PLEKHA1	2.22	1.49–3.31	46.78	.0002	*1.77*	*33.08*	2.21	1.49–3.29	20.46	<.0001	3.31	49.88
*rs12258692* (2)	PLEKHA1	…	…	…	…	…	…	…	…	…	…	…	…
*rs4405249* (1)	PLEKHA1	.62	.33–1.15	−12.96	.1692	.61	−12.69	.87	.1–7.56	−.23	1	.77	−.57
*rs1045216* (2)	PLEKHA1	.48	.32–.74	−51.23	.0005	*.49*	*−18.27*	.37	.21–.65	−14.3	.0003	.28	−35.68
rs1882907 (2)		*.58*	.4–.84	*−16.73*	.0026	.44	−5.79	*.31*	.1–.97	*−2.37*	.0438	*.27*	*−3.65*
*rs10490923* (2)	LOC387715	*.53*	.31–.9	*−13.27*	.0239	.34	−9.01	.22	.04–1.09	−2.51	.0809	.2	−3.32
*rs2736911* (2)	LOC387715	.72	.42–1.21	−6.92	.2552	1.47	1.99	1.1	.13–9.53	.1	1	1.03	.04
*rs10490924* (2)	LOC387715	5.03	3.2–7.91	57.11	<.0001	*2.72*	*22.76*	5.75	2.46–13.46	21.2	<.0001	10.57	42.71
*rs11538141* (2)	PRSS11	…	…	…	…	…	…	…	…	…	…	…	…
rs760336 (2)	PRSS11	*.64*	.44–.93	*−35.37*	.013	.8	−6.95	.69	.46–1.03	−7.95	.0773	*.55*	*−26.43*
rs763720 (1)	PRSS11	*1.69*	1.2–2.38	*21.24*	.0018	*1.55*	*16.95*	*2.63*	1.1–6.25	*5.17*	.0277	*3.16*	*10.14*
*rs1803403* (1)	PRSS11	*2.98*	1.25–7.06	*10.51*	.0093	*2.98*	*10.51*	…	…	…	…	…	…

Note.— Type A–affected individuals are compared with controls. OR and AR values are underlined if corresponding P values are ⩽.001 and are in bold italics if P values are ⩽.05. Allele denotes the risk allele (minor allele in controls). RR = homozygotes for the risk allele; RN = heterozygotes for the risk allele; NN = homozygotes for the normal allele. Locally typed SNPs are in bold italics. Blank spaces separate the three chromosomal regions corresponding to SNPs in and around CFH, GRK5/RGS10, and PLEKHA1/LOC687715/PRSS11.