Table 5.
Top Results from the Linkage Analysis
Chromosome | MLS | SiblingAllele Sharing(%) | λs |
6p21 | 11.66 | 58.5 | 1.51 |
17q23 | 2.45 | 53.8 | 1.18a |
5q33 | 2.18 | 54.0 | 1.19a |
20p12 | 1.83 | 54.0 | 1.09a |
3p26 | 1.74 | 53.4 | 1.16a |
Since the evidence for linkage at these loci is not statistically robust, these estimates provided upper limits for the size of effects attributable to underlying susceptibility factors (Terwilliger et al. 2002).