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. Author manuscript; available in PMC: 2005 Sep 23.
Published in final edited form as: J Biol Chem. 2005 Feb 4;280(14):14057–14069. doi: 10.1074/jbc.M414401200

Figure 6. Hierarchical cluster image of genes rescued by Wt. IKKα in comparison to an IKKα(K44M) mutant.

Figure 6

Signal values of the 118 genes rescued by Wt. IKKα in duplicate screens (columns 1 and 2) were evaluated by hierarchical clustering (as described in Figure 3) in comparison to their signal values in duplicate screens of 2 hr TNFα (2T) stimulated IKKα (−/−) MEFs expressing a kinase inactive IKKα(K44M) mutant (columns 3 and 4). As in Figure 4, the IKKα specificities of the rescues can be visualized in columns 5 and 6, which display the signal values of the 118 genes in IKKα(−/−) null MEFs or the same cells expressing an empty retroviral (EV).

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