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Frequency controls oscillatory behavior in LC from adult animals. (A) Recordings from a pair of neurons in a slice from an adult in control (spontaneous frequency, middle traces) and when the excitability was increased (traces on left, muscarine at 10 μM) or decreased (traces on right, TTX at 1 μM). (B) Cross-correlogram of the recordings under these experimental conditions. Note the dramatic changes in rhythm and synchrony.
