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. 2025 Jun 18;37:100741. doi: 10.1016/j.ynstr.2025.100741

Table 2.

Clinical and demographic baseline characteristics of study participants.

Transmasculine (TM) group Transfeminine (TF) group
Sample size in total cohort 11 7
Age a Mean (SD) 21.3 (2.5) 28.0 (5.6)
Alcohol (consumptions per week) Mean (SD) 0.4 (0.6) 0.8 (1.9)
Smoking (n, %) Never 8 (72 %) 7 (100 %)
Previous 2 (18 %) 0 (0 %)
Current 1 (9 %) 0 (0 %)
Psychotropic medication use at baseline (n, %) Antidepressants 2 (18 %) 1 (14.2 %)
Anxiolytics 0 (0 %) 0 (0 %)
Stimulants 2 (18 %) 0 (0 %)
Antipsychotics 0 (0 %) 0 (0 %)
Perceived Stress Score at baseline Mean (SD) 12.9 (6.8) 12.6 (8.8)
Cycle regulation use at baseline (n, %) b 4 (36 %)
Form of testosterone prescribed at start of GAHT (n, %) Testosterone gel 8 (73 %)
Short-acting injections 3 (27 %)
Long-acting injections 0 (0 %)
Form of estrogen prescribed at start of GAHT (n, %) Estradiol tablets 6 (86 %)
Estradiol patches 1 (14 %)
Form of anti-androgens prescribed at start of GAHT (n, %)
GnRH analogues 7 (100 %)
a

The transmasculine group was significantly younger than the transfeminine group (p = 0.018).

b

2 participants used intramuscular medroxyprogesterone injections, 1 used lynestrenol tablets, 1 had a medroxyprogesterone implant.