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. 2025 Jul 15;15(7):e093362. doi: 10.1136/bmjopen-2024-093362

Table 3. Unweighted logistic regression analysis on the association between LE8 score and stroke in sensitive analysis.

Non-adjusted model P value Model I P value Model II P value
OR (95% CI) OR (95% CI) OR (95% CI)
LE8 score
 High (≥80) Reference Reference Reference
 Moderate (50–79) 4.31 (3.81 to 6.01) <0.001 2.64 (1.94 to 3.70) <0.001 2.21 (1.62 to 3.12) <0.001
 Low (LE8 <50) 12.1 (8.79 to 17.0) <0.001 6.28 (4.55 to 8.89) <0.001 4.60 (3.30 to 6.57) <0.001
Health behaviours score
 High (≥80) Reference Reference Reference
 Moderate (50–79) 1.79 (1.48 to 2.18) <0.001 1.82 (1.49 to 2.22) <0.001 1.61 (1.32 to 1.97) <0.001
 Low (LE8 <50) 3.65 (2.99 to 4.48) <0.001 3.78 (3.08 to 4.65) <0.001 2.93 (2.37 to 3.64) <0.001
Health factors score
 High (≥80) Reference Reference Reference
 Moderate (50–79) 2.86 (2.33 to 3.53) <0.001 1.41 (1.15 to 1.76) 0.02 1.35 (1.09 to 1.68) 0.006
 Low (LE8 <50) 5.60 (4.51 to 6.99) <0.001 2.29 (1.83 to 2.88) <0.001 2.02 (1.61 to 2.55) <0.001

Model I: adjusted for age and gender.

Model II: additionally adjusted for race/ethnicity, education, marital status and family income ratio.

LE8, Life’s Essential 8.