Table 1. Clinicopathological characteristics of HNSCC patients in cohort 1.
| Clinicopathological characteristics | Values |
|---|---|
| Age (years) | 65.09±8.57 |
| <60 | 39 (24.5) |
| ≥60 | 120 (75.5) |
| Sex | |
| Male | 153 (96.2) |
| Female | 6 (3.8) |
| Primary subsites | |
| Larynx | 121 (76.1) |
| Hypopharynx | 38 (23.6) |
| Smoking | |
| No | 27 (17.0) |
| Yes | 132 (83.0) |
| Alcohol | |
| No | 74 (46.5) |
| Yes | 85 (53.5) |
| Diabetes | |
| No | 149 (93.7) |
| Yes | 10 (6.3) |
| Hypertension | |
| No | 101 (63.5) |
| Yes | 58 (36.5) |
| cT staging | |
| 1 | 4 (2.5) |
| 2 | 42 (26.4) |
| 3 | 65 (40.9) |
| 4 | 48 (30.2) |
| Pathological nodal metastasis | |
| Absent | 95 (59.7) |
| Present | 64 (40.3) |
| Ki-67 (%) | |
| <60 | 96 (60.4) |
| ≥60 | 43 (27.0) |
| Not stained | 20 (12.6) |
| p53 | |
| No | 55 (34.6) |
| Yes | 66 (41.5) |
| Not stained | 38 (23.9) |
| p16 | |
| No | 74 (46.5) |
| Yes | 33 (20.8) |
| Not stained | 52 (32.7) |
| IL-32 expression | 0.06±0.02 |
| F. nucleatum enrichment | |
| Low | 40 (25.2) |
| High | 116 (73.0) |
| Not stained | 3 (1.9) |
Data are presented as n (%) or mean ± SD. cT staging, clinical T staging; p53, tumor protein p53; F. nucleatum, Fusobacterium nucleatum; HNSCC, head and neck squamous cell carcinoma; Ki-67, antigen Kiel 67; p16 (P16INK4; CDKN2A), cyclin dependent kinase inhibitor 2A; SD, standard deviation.