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. 2025 Jul 14;21(1):2512656. doi: 10.1080/21645515.2025.2512656

Table 1.

Top 10 most cited literature in TAMs and CRC research.

Rank Title DOI First Author Year Journal Citations (as of August 9, 2024) Average per Year
1 Cancer-related inflammation 10.1038/nature07205. Mantovani, Alberto 2008 NATURE 8,468 529.25
2 Inflammation and Cancer: Triggers, Mechanisms, and Consequences 10.1016/j.immuni.2019.06.025. Greten, Florian R. 2019 IMMUNITY 1,966 393.20
3 PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity 10.1038/nature22396. Gordon, Sydney R. 2017 NATURE 1,424 203.43
4 Roles of the immune system in cancer: from tumor initiation to metastatic progression 10.1101/gad.314617.118. Gonzalez, Hugo 2018 GENES & DEVELOPMENT 1,204 200.67
5 Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis 10.1038/nrgastro.2017.119. Jia, Wei 2018 NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY 1,049 174.83
6 Immunotherapy in colorectal cancer: rationale, challenges and potential 10.1038/s41575-019-0126-x. Ganesh, Karuna 2019 NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY 995 199.00
7 The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy 10.1038/s41568-020-0285-7. Bruni, Daniela 2020 NATURE REVIEWS CANCER 838 209.50
8 Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer 10.1016/j.cell.2020.03.048. Zhang, Lei 2020 CELL 703 175.75
9 Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature 10.1371/journal.pone.0050946. Zhang, Qiong-wen 2012 PLOS ONE 676 56.33
10 Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy 10.1186/s40425-017-0257-y. Cannarile, Michael A. 2017 JOURNAL FOR IMMUNOTHERAPY OF CANCER 662 94.57

Table 1 lists the 10 most highly cited publications in the field of TAMs and CRC and shows their links, years, and journals.