Figure 8.

Two routes to partial shell-filled tecto(dendrimers). Route I involves amidation of a limited amount of nucleophilic core dendrimer with an excess of electrophilic shell dendrimer reagent to produce reactive (PS:CST)-[D_c-N-X]-amide-{D_s-E-Y}_n. These products may be pacified by reacting with EA or Tris(hydroxymethyl) aminomethane (Tris) to produce shell-pacified-(PS:CST)-[D_c-N-X]-amide-{D_s-E-Z}_n. Route II involves amidation of a limited amount of electrophilic core dendrimer with an excess of nucleophilic shell dendrimer reagent to produce reactive-(PS:CST)-[D_c-E-X]-amide-{D_s-N-X}_n. These products may be converted to pacified forms by reacting with EA or an excess of EDA to produce core pacified-(PS:CST)-[D_c-E-Z]-amide-{D_s-N-X}_n.