Table 2.

PS reactive: CST; mass/shell filling analysis

	Compound 5	Compound 6	Compound 7	Compound 8
Formula
[Dc-E-Y]-amide-{Ds-N-X}n†	[Dc4.5Y]-amide-{Ds3.0X}n*	[Dc4.5Y]-amide-{Ds3.0X}n**	[Dc4.5Y]-amide-{Ds4.0X}n*	[Dc4.5Y]-amide-{Ds5.0X}n*
MW (calculated) for saturated shell‡	173,915	140,133	202,352	255,847
Number of shell tectons observed§/  theoretical¶	12/21	14/23	3–4/12‖	2–3/8‡‡
% Shell filling	65	62	36	33
PAGE (MW)	114,500	87,340	73,500	84,000

^† In the notation [D_c-E-Y]-amide-{D_s-N-X}_n, n = number of dendrimer shell molecules {D_s-N-X} surrounding the dendrimer core molecule [D_c-E-Y], where [D_c-E-Y] represents carboxymethyl ester-terminated, [EDA* or NH₃**], generation E, PAMAM dendrimer core reagent and {D_s-N-X} represents amine-terminated, [EDA* or NH₃**] core, generation N, PAMAM dendrimer shell reagent. 

^‡ MW of theoretical number of shell dendrimer tectons plus core tecton, as determined from MALDI-TOF-MS data for individual core and shell tecton MWs. Values used for n in these calculations were obtained by using the Mansfield–Tomalia–Rakesh equation as described (48, 50), or when r₁/r₂ < 1.2 then 

^‖r₁/r₂ = 1.1 (shell saturation = 12), 

^‡‡r₁/r₂ = 0.72 (shell saturations = 8). 

^§ Based on the experimental PAGE MWs of the reactive tecto(dendrimer)s as observed in crude reaction mixture after partial removal of excess shell reagent. 

^¶ The theoretical number (n) of dendrimer shell molecules that would be expected to surround a specific dendrimer core molecule according to the Mansfield–Tomalia–Rakesh equation or when r₁/r₂ < 1.2 (48, 50).